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Our Mission

The Bureau is dedicated to three mutually reinforcing efforts:

(1) Strengthening nonproliferation regimes:

ISN uses bilateral and multilateral diplomacy to prevent proliferation; to promote the highest possible standards of nuclear safety, security, and safeguards worldwide; and to ensure effective nonproliferation protections in civil-nuclear cooperation programs;

(2) Shaping the security environment:

ISN shapes the security environment to reduce WMD-related threats by promoting regional security and deterrence initiatives and strategic stability dialogues, implementing counterproliferation efforts and policies, vigorously enforcing WMD-related sanctions, and using sanctions pressures and diplomatic outreach to undermine destabilizing Russian arms trade and intelligence partnerships; and

(3) Counter-threat programming:

ISN develops and administers capacity-building and other programs and initiatives to reduce proliferation risks, improve export controls, counter nuclear smuggling, keep WMD out of the hands of terrorists, improve nuclear safety and security around the world, and address urgent threat-reduction and weapons-elimination challenges worldwide.

Our Organization

The ISN bureau consists of three main organizational components, each managed at the Deputy Assistant Secretary (DAS) level. Each DAS reports to Assistant Secretary of State C.S. Eliot Kang through Principal Deputy Assistant Secretary of State Ann Ganzer. The Assistant Secretary oversees operations of the bureau and reports to the Under Secretary of State for Arms Control and International Security, the Deputy Secretary of State, and the Secretary of State. The ISN Office of the Executive Director (ISN/EX), headed by Sonna Stampone, reports to Assistant Secretary Kang. ISN’s Chief of Staff is T. Seth Morrell.

Principal Deputy Assistant Secretary (PDAS) Ann K. Ganzer is a career member of the Senior Executive Service and is responsible for overall bureau management operations, oversees two offices and manages strategic planning for ISN.

  • The Office of Congressional and Public Affairs (CPA) supports ISN interactions with Congress, media, industry, academia, and NGOs, as well as coordinating public diplomacy, strategic messaging, and other outreach efforts in support of all ISN missions.
  • The Office of Policy Coordination (PC) works with a range of offices in ISN and with other Department stakeholders to ensure that nonproliferation tools and priorities are fully leveraged in the development of policy options.

Deputy Assistant Secretary Anthony Wier serves as DAS for Nonproliferation Policy, overseeing three ISN offices principally charged with advancing U.S. Government efforts related to nuclear nonproliferation and biological weapons threats.

  • The Office of Multilateral Nuclear and Security Affairs (MNSA) formulates and directs U.S. policy related to the Nuclear Nonproliferation Treaty, the International Atomic Energy Agency, safeguards on excess fissile material, and other multilateral nuclear issues such as fissile material production moratoria and the various international security challenges presented by Iran’s nuclear program.
  • The Office of Nuclear Energy, Safety, and Security (NESS) develops U.S. policy on peaceful nuclear cooperation, the future of the international fuel cycle, nuclear safety, export controls, and the physical protection of nuclear materials and facilities.

Deputy Assistant Secretary Gonzalo Suarez serves as DAS for International Security Policy. In this capacity, he oversees ISN’s four offices responsible for shaping the security environment through sanctions enforcement; through regional security, deterrence, and strategic stability dialogues; and through other such diplomatic initiatives.

  • The Office of Conventional Arms Threat Reduction (CATR) leads U.S. efforts in the Wassenaar Arrangement to curb the proliferation of destabilizing conventional weapons and related dual-use technologies, including advanced Man-Portable Air Defense Systems, precision-guided munitions, aircraft, missiles, sensors, and lasers.
  • The Office of Counterproliferation Initiatives (CPI) implements efforts to interdict shipments of WMD and their means of delivery, to disrupt and shut down proliferator procurement and financial networks, promote observance of UNSCR 1540, ensure compliance with UN Security Council WMD-related sanctions, impose nonproliferation-related U.S. sanctions, lead implementation of Section 231 of the Countering America’s Adversaries Through Sanctions Act of 2017 (CAATSA), and support and strengthen the Proliferation Security Initiative.
  • The Office of Missile, Biological, and Chemical Nonproliferation (MBC)leads our efforts in the Missile Technology Control Regime (MTCR) and the Hague Code of Conduct (HCOC) to combat the proliferation of missiles capable of delivering, impedes proliferation of chemical and biological weapons (via the Australia Group), and coordinates interdictions, key aspects of national security export control and visa implementation, and related sanctions.
  • The Office of Competitive Strategy (CS) develops and implements foreign policy designed to protect U.S. critical technologies.  CS coordinates Bureau efforts within the Department on competitive diplomacy initiatives to counter the malign influence and destabilizing behavior of competitive powers in the international security arena, while developing and implementing policies that shape the international security environment by protecting America’s technological and military advantage, and denying, delaying, and disrupting adversaries.

Acting Deputy Assistant Secretary Kathryn Insley serves as DAS for International Security and Nonproliferation Programs. In this capacity, she oversees ISN’s four offices responsible for counter-threat programming, charged with developing and implementing capacity-building and other programs in support of ISN’s missions.

  • The Office of Cooperative Threat Reduction (CTR) assists other countries in securing biological, chemical, and nuclear materials, technology, and expertise worldwide via the Global Threat Reduction Program.
  • The Office of Export Control Cooperation (ECC) assists other countries in improving strategic trade control systems via the Export Control and Related Border Security program, and coordinates and strengthens U.S. government nonproliferation export control assistance efforts for other countries.
  • The Office of Weapons of Mass Destruction Terrorism (WMDT) develops policies and plans, directs initiatives, and coordinates capacity-building activities to prevent, protect against, and respond to the threat or use of chemical, biological, nuclear and radiological weapons, including: the Global Initiative to Combat Nuclear Terrorism; counter-nuclear-smuggling initiatives; responses to nuclear trafficking; and support for foreign consequence management of chemical, biological, radiological, or nuclear incidents.
  • The Nonproliferation and Disarmament Fund (NDF) uses its agile and flexible funding and implementation authorities to respond to unanticipated or unusually challenging opportunities, such as missile destruction or removal of fissile material, in support of the most urgent nonproliferation, counterproliferation, or disarmament priorities.

ISN is a talented, diverse, and hard-working team of experts drawn from a range of Civil Service, Foreign Service, technical, academic, military, private sector, Congressional, and other professional backgrounds. Its staff is dedicated to using their skills and experience to meet some of the most significant and daunting security threats the U.S. and international community face today. We in ISN are proud to serve our country, protect the American people, and make the world safer and more secure for all.

U.S. Department of State

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